Substitution of Oral Fluoropyrimidines for Infusional Fluorouracil With Radiotherapy: How Much Data Do We Need?

Author:

Crane Christopher H.1,Sargent Daniel J.2

Affiliation:

1. Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX

2. Division of Biostatistics, Mayo Clinic Cancer Center, Rochester, MN

Publisher

American Society of Clinical Oncology (ASCO)

Subject

Cancer Research,Oncology

Reference24 articles.

1. Improving Adjuvant Therapy for Rectal Cancer by Combining Protracted-Infusion Fluorouracil with Radiation Therapy after Curative Surgery

2. Smalley S, Benedetti J, Williamson S, et al: Intergroup 0144-phase III trial of 5-FU based chemotherapy regimens plus radiotherapy (XRT) in postoperative adjuvant rectal cancer: Bolus 5-FU vs prolonged venous infusion (PVI) before and after XRT + PVI vs bolus 5-FU + leucovorin (LV) + levamisole before and after XRT + bolus 5-FU + LV. Proc Am Soc Clin Oncol 22:251,2003, (abstr 1006)

3. Adjuvant postoperative fluorouracil-modulated chemotherapy combined with pelvic radiation therapy for rectal cancer: initial results of intergroup 0114.

4. Phase I Trial Evaluating the Concurrent Combination of Radiotherapy and Capecitabine in Rectal Cancer

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