The Simpleton’s Error in Drug Development

Author:

Castro Michael1

Affiliation:

1. The Charles Wood Cancer Center, Glens Falls, NY

Publisher

American Society of Clinical Oncology (ASCO)

Subject

Cancer Research,Oncology

Reference4 articles.

1. Influence of Unrecognized Molecular Heterogeneity on Randomized Clinical Trials

2. Fukuoka M, Yano S, Giaccone G, et al: Final results from a phase II trial of ZD1839 (’Iressa’) for patients with advanced non-small-cell lung cancer (IDEAL 1). Proc Am Soc Clin Oncol 21: 298a,2002 (abstr 1188)

3. Kris MG, Natale RB, Herbst RS, et al: A phase II trial of ZD1839 (’Iressa’) in advanced non-small cell lung cancer (NSCLC) patients who had failed platinum- and docetaxel-based regimens (IDEAL 2). Proc Am Soc Clin Oncol 21: 292a,2002 (abstr 1166)

4. Ruckdeschel JC, Simon G, Antonia S, et al: ZD1839 (’Iressa’) as a single agent for the treatment of metastatic non-small-cell lung cancer. Proc Am Soc Clin Oncol 21: 318a,2002 (abstr 1269)

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