Misuse of Noninferiority Margin: How Much Margin Is Ethical?
Author:
Affiliation:
1. Vinod Sharma, MD, DM, and Akash Kumar, MD, DM, Department of Medical Oncology, National Cancer Institute, Jhajjar, India
Publisher
American Society of Clinical Oncology (ASCO)
Subject
Cancer Research,Oncology
Link
https://ascopubs.org/doi/pdfdirect/10.1200/JCO.20.02772
Reference9 articles.
1. Randomized Comparison of Pazopanib and Doxorubicin as First-Line Treatment in Patients With Metastatic Soft Tissue Sarcoma Age 60 Years or Older: Results of a German Intergroup Study
2. Challenges in the Design and Interpretation of Noninferiority Trials
3. Efficacy of experimental treatments compared with standard treatments in non-inferiority trials: a meta-analysis of randomized controlled trials
4. A phase II trial comparing pazopanib with doxorubicin as first-line treatment in elderly patients with metastatic or advanced soft tissue sarcoma (EPAZ): study protocol for a randomized controlled trial
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