Comprehensive Discussions on KIT ATP-Binding Pocket/Activation Loop Mutations in Ripretinib Resistance
Author:
Affiliation:
1. Yanzhe Xia, MSc, Department of Pharmacy, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; and Xinhua Zhang, MD, Center for Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
Publisher
American Society of Clinical Oncology (ASCO)
Link
https://ascopubs.org/doi/pdfdirect/10.1200/JCO.24.00673
Reference3 articles.
1. KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape
2. Sunitinib-resistant gastrointestinal stromal tumors harbor cis-mutations in the activation loop of the KIT gene
3. Circulating tumor DNA analysis of the phase III VOYAGER trial: KIT mutational landscape and outcomes in patients with advanced gastrointestinal stromal tumor treated with avapritinib or regorafenib
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