Evolution and Current Status of the Multidisciplinary Management of Locally Advanced Rectal Cancer

Author:

Deschner Benjamin W.1ORCID,VanderWalde Noam A.2ORCID,Grothey Axel2ORCID,Shibata David1ORCID

Affiliation:

1. Division of Surgical Oncology, Department of Surgery, University of Tennessee Health Science Center, Memphis, TN

2. Radiation Oncology and Medical Oncology, West Cancer Center and Research Institute, Memphis, TN

Abstract

The management of locally advanced rectal cancer has grown in both complexity and quality since the first proctectomy. What once was a malignancy with a fairly consistent treatment algorithm for decades, a recent paradigm shift in the care of these patients has led to a more personalized, multidisciplinary approach with variations in timing, sequence, duration, and potential exclusion of multimodality therapies. This review summarizes the most important evidence behind these developing overarching concepts to provide a context for this paradigm shift.

Publisher

American Society of Clinical Oncology (ASCO)

Subject

Oncology(nursing),Health Policy,Oncology

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