First-in-human phase I safety, pharmacokinetic (PK), and pharmacodynamic (PD) analysis of the oral MEK-inhibitor AS703026 (two regimens [R]) in patients (pts) with advanced solid tumors.-Reference-Cited by-同舟云学术

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First-in-human phase I safety, pharmacokinetic (PK), and pharmacodynamic (PD) analysis of the oral MEK-inhibitor AS703026 (two regimens [R]) in patients (pts) with advanced solid tumors.

Published:2010-05-20 Issue:15_suppl Volume:28 Page:2504-2504
ISSN:0732-183X
Container-title:Journal of Clinical Oncology
language:en
Short-container-title:JCO

Author:

Delord J.,Houede N.,Awada A.,Taamma A.,Faivre S. J.,Besse-Hammer T.,Italiano A.,Vignaud C.,Donica M.,Raymond E.

Publisher

American Society of Clinical Oncology (ASCO)

Subject

Cancer Research,Oncology

Link

http://ascopubs.org/doi/pdfdirect/10.1200/jco.2010.28.15_suppl.2504

Cited by 22 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Randomised phase II trial (SWOG S1310) of single agent MEK inhibitor trametinib Versus 5-fluorouracil or capecitabine in refractory advanced biliary cancer;European Journal of Cancer;2020-05

2. Clinical update on K-Ras targeted therapy in gastrointestinal cancers;Critical Reviews in Oncology/Hematology;2018-10

3. P53 and MITF/Bcl-2 identified as key pathways in the acquired resistance of NRAS-mutant melanoma to MEK inhibition;European Journal of Cancer;2017-09

4. Targeting RAS signaling pathway as a potential therapeutic target in the treatment of colorectal cancer;Journal of Cellular Physiology;2017-05-23

5. A phase 1 dose-escalation and expansion study of binimetinib (MEK162), a potent and selective oral MEK1/2 inhibitor;British Journal of Cancer;2017-02

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