ESPAC-4: A multicenter, international, open-label randomized controlled phase III trial of adjuvant combination chemotherapy of gemcitabine (GEM) and capecitabine (CAP) versus monotherapy gemcitabine in patients with resected pancreatic ductal adenocarcinoma.

Author:

Neoptolemos John P.1,Palmer Dan1,Ghaneh Paula1,Valle Juan W.2,Cunningham David3,Wadsley Jonathan4,Meyer Tim5,Anthoney Alan6,Glimelius Bengt7,Falk Stephen8,Segersvard Ralf9,Izbicki Jakob R.10,Middleton Gary William11,Ross Paul J.12,Wasan Harpreet13,Mcdonald Alec14,Crosby Tom David Lewis15,Psarelli Eftychia Eirini1,Hammel Pascal16,Buchler Markus W.17

Affiliation:

1. University of Liverpool, Liverpool, United Kingdom;

2. Department of Medical Oncology, The Christie NHS Foundation Trust; University of Manchester, Manchester, United Kingdom;

3. Royal Marsden Hospital, Surrey, United Kingdom;

4. Weston Park Hospital, Sheffield, United Kingdom;

5. UCL Cancer Institute, University College London,, London, United Kingdom;

6. Leeds Cancer Research UK Clinical Centre, Leeds, United Kingdom;

7. Uppsala University, Uppsala, Sweden;

8. Bristol Haematology and Oncology Centre, Bristol, United Kingdom;

9. Karolinska Institute, Stockholm, Sweden;

10. University Medical Center Hamburg-Eppendorf, Hamburg, Germany;

11. University of Birmingham, Surrey, United Kingdom;

12. Guy's Hospital, London, United Kingdom;

13. Hammersmith Hospital, Imperial College, London, United Kingdom;

14. Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom;

15. Velindre Cancer Centre, Cardiff, United Kingdom;

16. Hôpital Beaujon, Clichy, France;

17. University of Heidelberg, Heidelberg, Germany;

Publisher

American Society of Clinical Oncology (ASCO)

Subject

Cancer Research,Oncology

Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. The Prognosis Value of PIWIL1 and PIWIL2 Expression in Pancreatic Cancer;Journal of Clinical Medicine;2019-08-22

2. Pancreatic Cancer and Possible Therapeutic Options;Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy;2019

3. Evolution of Pancreatic Cancer Surgery;Pancreatic Cancer;2017

4. Clinical practice guidelines — what is the evidence?;Nature Reviews Clinical Oncology;2016-08-17

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