PHOCUS: A phase 3 randomized, open-label study comparing the oncolytic immunotherapy Pexa-Vec followed by sorafenib (SOR) vs SOR in patients with advanced hepatocellular carcinoma (HCC) without prior systemic therapy.

Author:

Abou-Alfa Ghassan K.1,Galle Peter R.2,Chao Yee3,Brown Karen T.1,Heo Jeong4,Borad Mitesh J.5,Luca Angelo6,Pelusio Adina7,Agathon Delphine8,Lusky Monika8,Breitbach Caroline7,Burke James7,Qin Shukui9

Affiliation:

1. Memorial Sloan Kettering Cancer Center, New York, NY;

2. University Medical Center Mainz, Mainz, Germany;

3. Taipei Veterans General Hospital, Taipei City, Taiwan;

4. Pusan National University Hospital, Busan, South Korea;

5. Mayo Clinic, Scottsdale, AZ;

6. IRCCS-ISMETT – University of Pittsburgh Medical Center (UPMC), Palermo, Italy;

7. Sillajen, Inc, San Francisco, CA;

8. Transgene S.A., Illkirch-Graffenstaden, France;

9. Medical Oncology Department, Nanjing Bayi Hospital, Nanjing, China;

Publisher

American Society of Clinical Oncology (ASCO)

Subject

Cancer Research,Oncology

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