1. Department of Clinical and Molecular Medicine, Sapienza University Sant' Andrea Hospital, Rome, Italy;
2. Unit of Human Microbiome, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy;
3. Department of Experimental Medicine, Sapienza University Policlinico Umberto 1, Rome, Italy;
4. Sant'Andrea Hospital, Rome, Italy;
5. S. Andrea Hospital, Sapienza University of Rome, Rome, Italy;