Brigatinib (BRG) in crizotinib (CRZ)-refractory ALK+ non–small cell lung cancer (NSCLC): Efficacy updates and exploratory analysis of CNS ORR and overall ORR by baseline (BL) brain lesion status.

Author:

Huber Rudolf M.1,Kim Dong-Wan2,Ahn Myung-Ju3,Langer Corey J.4,Tiseo Marcello5,West Howard6,Groen Harry J.M.7,Reckamp Karen L.8,Hochmair Maximilian J.9,Leighl Natasha B.10,Holmskov Hansen Karin11,Gettinger Scott N.12,Paz-Ares Luis G.13,Kim Edward S.14,Smit Egbert F.15,Kim Sang-We16,Reichmann William17,Kerstein David17,Camidge D. Ross18

Affiliation:

1. University Hospital of Munich, Thoracic Oncology Centre Munich, Munich, Germany;

2. Seoul National University Hospital, Seoul, Korea, Republic of (South);

3. Samsung Medical Center, Seoul, Korea, Republic of (South);

4. University of Pennsylvania Perelman School of Medicine, Philadelphia, PA;

5. Medical Oncology Unit, University Hospital of Parma, Parma, Italy;

6. Swedish Cancer Institute, Seattle, WA;

7. University of Groningen, University Medical Center Groningen, Groningen, Netherlands;

8. City of Hope Comprehensive Cancer Center, Duarte, CA;

9. Otto Wagner Hospital, Vienna, Austria;

10. Princess Margaret Cancer Centre, Toronto, ON, Canada;

11. Department of Oncology, Odense University Hospital, Odense, Denmark;

12. Yale Cancer Center, New Haven, CT;

13. University Hospital 12 de October, Madrid, Spain;

14. Levine Cancer Institute, Atrium Health, Charlotte, NC;

15. VU University Medical Center, Amsterdam, Netherlands;

16. Asan Medical Center, Seoul, Korea, Republic of (South);

17. Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Cambridge, MA;

18. University of Colorado Cancer Center, Aurora, CO;

Publisher

American Society of Clinical Oncology (ASCO)

Subject

Cancer Research,Oncology

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