A pH-responsive amphiphilic chitosan–pyranine core–shell nanoparticle for controlled drug delivery, imaging and intracellular pH measurement

Author:

Chou Hao-Syun123,Hsiao Meng-Hsuan123,Hung Wei-Yang123,Yen Tin-Yo4567,Lin Hui-Yi8910,Liu Dean-Mo123

Affiliation:

1. Department of Materials Science and Engineering

2. National Chiao Tung University

3. Hsinchu, Taiwan

4. Joint Honours of Biotechnology

5. Department of Microbiology and Immunology

6. University of British Columbia/British Columbia Institute of Technology

7. Vancouver, Canada

8. School of Pharmacy

9. China Medical University

10. TaiChung, Taiwan

Abstract

A new type of CHC–PY core–shell nanoparticle provides multiple functionality, where a synergistic performance of nanotherapeutics, imaging and even diagnosis at a cellular resolution can be achieved simultaneously.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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