Biophysical investigation of thymoquinone binding to ‘N’ and ‘B’ isoforms of human serum albumin: exploring the interaction mechanism and radical scavenging activity

Author:

Ishtikhar Mohd1234,Rabbani Gulam1234,Khan Shawez5674,Khan Rizwan Hasan1234

Affiliation:

1. Interdisciplinary Biotechnology Unit

2. Aligarh Muslim University

3. Aligarh-202002

4. India

5. Department of Computer Science

6. Jamia Millia Islamia

7. New Delhi-110025

Abstract

Thymoquinone more strongly interacts with the ‘N’ isoform in comparison to the ‘B’ isoform of HSA and also increases its thermal stability but the antioxidant activity is significantly higher at the ‘B’ isoform of HSA.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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