Biophysical investigation of thymoquinone binding to ‘N’ and ‘B’ isoforms of human serum albumin: exploring the interaction mechanism and radical scavenging activity
Author:
Affiliation:
1. Interdisciplinary Biotechnology Unit
2. Aligarh Muslim University
3. Aligarh-202002
4. India
5. Department of Computer Science
6. Jamia Millia Islamia
7. New Delhi-110025
Abstract
Thymoquinone more strongly interacts with the ‘N’ isoform in comparison to the ‘B’ isoform of HSA and also increases its thermal stability but the antioxidant activity is significantly higher at the ‘B’ isoform of HSA.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C4RA09892G
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1. Thymoquinone in the clinical treatment of cancer: Fact or fiction?
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4. Chemical constituents of Plectranthus amboinicus and the synthetic analogs possessing anti-inflammatory activity
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