Carnosic acid ameliorated Aβ-mediated (amyloid-β peptide) toxicity, cholinergic dysfunction and mitochondrial defect in <i>Caenorhabditis elegans</i> of Alzheimer's Model-Reference-Cited by-同舟云学术

Carnosic acid ameliorated Aβ-mediated (amyloid-β peptide) toxicity, cholinergic dysfunction and mitochondrial defect in Caenorhabditis elegans of Alzheimer's Model

Published:2022 Issue:8 Volume:13 Page:4624-4640
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Chen Yun¹²,Wang Yarong¹²,Qin Qiao¹²,Zhang Yali¹²,Xie Lingling¹²,Xiao Jie¹²^ORCID,Cao Yong¹²^ORCID,Su Zuanxian³,Chen Yunjiao¹²^ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of Nutraceuticals and Functional Foods, College of Food Science, South China Agricultural University, Guangzhou 510640, Guangdong, China

2. Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510640, Guangdong, China

3. College of Horticulture, South China Agricultural University, Guangzhou 510640, Guangdong, China

Abstract

Carnosic acid reduced Aβ deposition and Aβ-mediated neurotoxicity, and ameliorated cholinergic dysfunction and mitochondrial disorders in the C. elegans model of Alzheimer's disease.

Funder

National Natural Science Foundation of China

Agriculture Research System of China

Ministry of Finance

Guangdong Province Introduction of Innovative R&D Team

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D1FO02965G

Reference82 articles.