Oxygen control: the often overlooked but essential piece to create better<i>in vitro</i>systems-Reference-Cited by-同舟云学术

Oxygen control: the often overlooked but essential piece to create betterin vitrosystems

Published:2022 Issue:6 Volume:22 Page:1068-1092
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Palacio-Castañeda Valentina¹^ORCID,Velthuijs Niels¹^ORCID,Le Gac Séverine²^ORCID,Verdurmen Wouter P. R.¹^ORCID

Affiliation:

1. Department of Biochemistry, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Geert Grooteplein 28, 6525 GA Nijmegen, The Netherlands

2. Applied Microfluidics for BioEngineering Research, MESA+ Institute for Nanotechnology & TechMed Centre, Organ-on-a-chip Centre, University of Twente, Postbus 217, 7500 AE Enschede, The Netherlands

Abstract

Variations in oxygen levels play key roles in numerous physiological and pathological processes, but are often not properly controlled inin vitromodels, introducing a significant bias in experimental outcomes.

Funder

Radboud Universitair Medisch Centrum

University of Twente

Health~Holland

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/LC/D1LC00603G

Reference177 articles.

1. Oxygenation in cell culture: Critical parameters for reproducibility are routinely not reported