Supplementation with <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> MH-022 for remission of motor impairments in a 6-OHDA-induced Parkinson's disease rat model by reducing inflammation, reshaping the gut microbiome, and fostering specific microbial taxa-Reference-Cited by-同舟云学术

Supplementation with Bifidobacterium animalis subsp. lactis MH-022 for remission of motor impairments in a 6-OHDA-induced Parkinson's disease rat model by reducing inflammation, reshaping the gut microbiome, and fostering specific microbial taxa

Published:2024 Issue: Volume: Page:
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Tsao Shu-Ping¹^ORCID,Yeh Tu-Hsueh²³,Lin Ya-Tin⁴⁵,Pan Chun-Hsu¹⁶^ORCID,Lee Yuan-Kun⁷,Wu Chieh-Hsi¹⁶,Huang Hui-Yu¹⁴⁵⁸⁹

Affiliation:

1. Ph.D. Program in Drug Discovery and Development Industry, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan

2. Department of Neurology, Taipei Medical University Hospital, Taipei 11031, Taiwan

3. School of Medicine, Taipei Medical University, Taipei 11031, Taiwan

4. Graduate Institute of Metabolism and Obesity Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, Taiwan

5. Nutrition Research Center, Taipei Medical University Hospital, Taipei 11031, Taiwan

6. School of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan

7. Department of Microbiology & Immunology, National University of Singapore, 22, Singapore 117597

8. Research Center for Digestive Medicine, Taipei Medical University Hospital, Taipei 11031, Taiwan

9. Neuroscience Research Center, Taipei Medical University, Taipei 11031, Taiwan

Abstract

Inflammation significantly influences the degeneration of dopaminergic neurons in Parkinson's disease (PD), which is potentially intensified by associated gut dysbiosis.

Funder

Ministry of Science and Technology, Taiwan

Ministry of Education

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D4FO02039A

Reference107 articles.

1. J.Meara and P.Hobson , Epidemiology of Parkinson's disease , in Parkinson's Disease in the Older Patient , 2018 , pp. 30–38

2. Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments

3. Non-motor symptoms in Parkinson's disease

4. Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis

5. The impact of reactive oxygen species and genetic mitochondrial mutations in Parkinson's disease