Reactions of CF3-enones with arenes under superelectrophilic activation: a pathway to trans-1,3-diaryl-1-CF3-indanes, new cannabinoid receptor ligands

Author:

Iakovenko Roman O.1234,Kazakova Anna N.1234,Muzalevskiy Vasiliy M.5674,Ivanov Alexander Yu.8910114,Boyarskaya Irina A.1234,Chicca Andrea1213141516,Petrucci Vanessa1213141516,Gertsch Jürg1213141516,Krasavin Mikhail1234,Starova Galina L.1234,Zolotarev Andrey A.1234,Avdontceva Margarita S.1234,Nenajdenko Valentine G.5674,Vasilyev Aleksander V.12345

Affiliation:

1. Institute of Chemistry

2. Saint-Petersburg State University

3. 198504 Saint-Petersburg

4. Russia

5. Department of Chemistry

6. Lomonosov Moscow State University

7. 119899 Moscow

8. Center for Magnetic Resonance

9. Research Park

10. St. Petersburg State University

11. Saint Petersburg

12. Institute of Biochemistry and Molecular Medicine

13. NCCR TransCure

14. University of Bern

15. 3012 Bern

16. Switzerland

Abstract

CF3-enones react with arenes in TfOH to givetrans-1,3-diaryl-1-CF3indanes.

Funder

Saint Petersburg State University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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