Synthesis of luminescent squaramide monoesters: cytotoxicity and cell imaging studies in HeLa cells-Reference-Cited by-同舟云学术

Synthesis of luminescent squaramide monoesters: cytotoxicity and cell imaging studies in HeLa cells

Published:2016 Issue:17 Volume:6 Page:14171-14177
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Fernández-Moreira Vanesa¹²³⁴⁵,Alegre-Requena Juan V.¹²³⁴⁵,Herrera Raquel P.⁶²³⁴⁵,Marzo Isabel⁷⁸⁴⁵,Gimeno M. Concepción¹²³⁴⁵

Affiliation:

1. Departamento de Química Inorgánica

2. Instituto de Síntesis Química y Catálisis Homogénea (ISQCH)

3. Universidad de Zaragoza-CSIC

4. E-50009 Zaragoza

5. Spain

6. Departamento de Química Orgánica

7. Departamento de Bioquímica y Biología Molecular y Celular

8. Universidad de Zaragoza

Abstract

Luminescent squaramide monoesters functionalised with fluorophore groups have been explored as cytotoxic and imaging agents. The biodistribution behaviour differs depending on the fluorescent moiety; lysosomal and nuclear localisation have been observed.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C5RA24521D

Reference38 articles.

1. Squaramides: physical properties, synthesis and applications

2. Squaramides: Bridging from Molecular Recognition to Bifunctional Organocatalysis

3. Bifunctional Amine-Squaramides: Powerful Hydrogen-Bonding Organocatalysts for Asymmetric Domino/Cascade Reactions

4. Be squared: expanding the horizon of squaric acid-mediated conjugations

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