Design, synthesis, and biological evaluation of novel carbazole aminothiazoles as potential DNA-targeting antimicrobial agents-Reference-Cited by-同舟云学术

Design, synthesis, and biological evaluation of novel carbazole aminothiazoles as potential DNA-targeting antimicrobial agents

Published:2016 Issue:10 Volume:7 Page:1988-1994
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Addla Dinesh¹²³⁴⁵,Wen Si-Qi¹²³⁴⁵,Gao Wei-Wei¹²³⁴⁵,Maddili Swetha Kameswari¹²³⁴⁵,Zhang Ling⁶⁷⁸⁵,Zhou Cheng-He¹²³⁴⁵

Affiliation:

1. Institute of Bioorganic & Medicinal Chemistry

2. School of Chemistry and Chemical Engineering

3. Southwest University

4. Chongqing 400715

5. PR China

6. School of Pharmacy

7. Yancheng Teachers University

8. Yancheng 224051

Abstract

Synthesis of a series of carbazole aminothiazoles as a new type of potential antimicrobial agents, and preliminary interactions with DNA indicated a possible intercalation mechanism.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C6MD00357E

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