Production of a promising modular proteinaceous self-assembled delivery system for vaccination-Reference-Cited by-同舟云学术

Production of a promising modular proteinaceous self-assembled delivery system for vaccination

Published:2023 Issue:25 Volume:15 Page:10794-10807
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Pan Chao¹,Ye Jingqin¹,Zhang Sen²,Li Xiang¹,Shi Yixin¹,Guo Yan¹,Wang Kangfeng¹³,Sun Peng¹⁴,Wu Jun¹,Wang Hengliang¹,Zhu Li¹^ORCID

Affiliation:

1. State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing, 100071, PR China

2. State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Millitary Medical Sciences, Beijing, 100071, PR China

3. College of Life Science, Hebei University, Baoding, 071002, PR China

4. School of Medicine, Tsinghua University, Beijing, 100084, PR China

Abstract

A proteinaceous nanovaccine chassis, self-assembled via fusion of two domains and a conjugate tag, was produced for binding biotinylated antigens. The nanovaccine could stimulate strong immune response, providing great prophylactic effects in mice.

Funder

National Natural Science Foundation of China

Beijing Nova Program

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NR/D2NR06718H

Reference105 articles.

1. Advances in mRNA Vaccines for Infectious Diseases

2. Why and How Vaccines Work

3. Predicting Vaccine Responsiveness

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