Selective Golgi α-mannosidase II inhibitors: N-alkyl substituted pyrrolidines with a basic functional group-Reference-Cited by-同舟云学术

Selective Golgi α-mannosidase II inhibitors: N-alkyl substituted pyrrolidines with a basic functional group

Published:2021 Issue:24 Volume:45 Page:10940-10951
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Klunda Tomáš¹²³⁴⁵,Hricovíni Michal¹²³⁴⁵,Šesták Sergej¹²³⁴⁵,Kóňa Juraj¹²³⁴⁵,Poláková Monika¹²³⁴⁵^ORCID

Affiliation:

1. Institute of Chemistry

2. Center for Glycomics

3. Slovak Academy of Sciences

4. SK-845 38 Bratislava

5. Slovakia

Abstract

Enzymatic assays, molecular modeling and NMR studies of novel 1,4-dideoxy-1,4-imino-l-lyxitols provided new information on the GH38 family enzyme inhibitors and their selectivity.

Funder

European Regional Development Fund

Agentúra Ministerstva Školstva, Vedy, Výskumu a Športu SR

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NJ/D1NJ01176F

Reference85 articles.

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3. P. Compain and O. R.Martin , Iminosugars: From Synthesis to Therapeutic Applications , Wiley , New York , 2007

4. Iminosugars past, present and future: medicines for tomorrow

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