Highly chemoselective difluoromethylative homologation of iso(thio)cyanates: expeditious access to unprecedented α,α-difluoro(thio)amides-Reference-Cited by-同舟云学术

Highly chemoselective difluoromethylative homologation of iso(thio)cyanates: expeditious access to unprecedented α,α-difluoro(thio)amides

Published:2019 Issue:86 Volume:55 Page:12960-12963
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Miele Margherita¹²³⁴,D’Orsi Rosarita⁵⁶⁷⁸,Sridharan Vellaisamy⁹¹⁰¹¹^ORCID,Holzer Wolfgang¹²³⁴,Pace Vittorio¹²³⁴^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry

2. University of Vienna

3. Vienna

4. Austria

5. Department of Sciences

6. University of Basilicata

7. 85100 Potenza

8. Italy

9. Department of Chemistry and Chemical Sciences

10. Central University of Jammu

11. India

Abstract

The new motif – α,α-difluoromethyl thioamide – has been assembled starting from isothiocyanate (as thioamide precursor) and a formal difluoromethyl-carbanion generated from commercially available TMSCHF₂.

Funder

Universität Wien

Università degli Studi della Basilicata

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CC/C9CC06929A

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