Insights into DNA catalysis from structural and functional studies of the 8-17 DNAzyme
Author:
Affiliation:
1. Chemical Sciences Department
2. Universidad Andres Bello
3. Santiago
4. Chile
5. Department of Chemistry
6. Life Sciences and Environmental Sustainability
7. University of Parma
8. Parma
9. Italy
Abstract
The review examines functional knowledge gathered over two decades of research on the 8-17 DNAzyme, focusing on three aspects: the structural requirements for catalysis, the role of metal ions and the participation of general acid-base catalysis.
Funder
Fondo Nacional de Desarrollo Científico y Tecnológico
Ministero dell’Istruzione, dell’Università e della Ricerca
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/OB/C9OB02453K
Reference83 articles.
1. A DNA enzyme that cleaves RNA
2. Mechanism and Utility of an RNA-Cleaving DNA Enzyme
3. A general purpose RNA-cleaving DNA enzyme
4. H. E. Ihms and Y.Lu , in Ribozymes: Methods and Protocols , ed. J. S. Hartig , Humana Press , Totowa, NJ , 2012 , pp. 297–316 , 10.1007/978-1-61779-545-9_18
5. In vitro selection, characterization, and application of deoxyribozymes that cleave RNA
Cited by 40 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Site-specific N-alkylation of DNA oligonucleotide nucleobases by DNAzyme-catalyzed reductive amination;Nucleic Acids Research;2024-07-25
2. Mechanochemical Activation of DNAzyme by Ultrasound;Advanced Science;2024-02
3. DNAzyme‐Catalyzed Site‐Specific N‐Acylation of DNA Oligonucleotide Nucleobases;Angewandte Chemie International Edition;2024-01-11
4. DNAzyme‐Catalyzed Site‐Specific N‐Acylation of DNA Oligonucleotide Nucleobases;Angewandte Chemie;2024-01-11
5. Exploring the catalytic mechanism of the 10–23 DNAzyme: insights from pH–rate profiles;Organic & Biomolecular Chemistry;2024
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3