Affinity-free enrichment and mass spectrometry analysis of the ovarian cancer biomarker CA125 (MUC16) from patient-derived ascites-Reference-Cited by-同舟云学术

Affinity-free enrichment and mass spectrometry analysis of the ovarian cancer biomarker CA125 (MUC16) from patient-derived ascites

Published:2021 Issue:1 Volume:146 Page:85-94
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Schuster-Little Naviya¹²³⁴^ORCID,Fritz-Klaus Roberta⁵⁶⁷⁴,Etzel Mark⁸⁶⁷⁴,Patankar Niharika⁵⁶⁷⁴,Javeri Saahil⁵⁶⁷⁴,Patankar Manish S.⁵⁶⁷⁴,Whelan Rebecca J.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry

2. University of Notre Dame

3. Notre Dame

4. USA

5. Department of Obstetrics and Gynecology

6. University of Wisconsin-Madison

7. Madison

8. Department of Food Science

Abstract

Developing a mass spectrometry-based assay for the ovarian cancer biomarker CA125 (MUC16) is a desirable goal, because it may enable detection of proteoforms that are analytically silent in the current immunoassay.

Funder

University of Notre Dame

National Cancer Institute

University of Wisconsin-Madison

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/AN/D0AN01701A

Reference30 articles.