Induction of transferrin aggregation by indazolium [tetrachlorobis(1H-indazole)ruthenate(iii)] (KP1019) and its biological function
Author:
Affiliation:
1. Department of Inorganic Chemistry
2. Faculty of Chemistry
3. Jagiellonian University
4. 30-387 Krakow
5. Poland
6. Jerzy Haber Institute of Catalysis and Surface Chemistry
7. Polish Academy of Sciences
8. 30-239 Krakow
Abstract
Pre-incubation ofKP1019with transferrin leads to the formation of adducts/aggregates, which inhibit the cytotoxic properties ofKP1019.
Funder
European Regional Development Fund
Narodowe Centrum Nauki
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,General Chemistry,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2019/NJ/C9NJ01342C
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1. Ru(II) Compounds: Next-Generation Anticancer Metallotherapeutics?
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