Microfluidic immunocapture of circulating pancreatic cells using parallel EpCAM and MUC1 capture: characterization, optimization and downstream analysis-Reference-Cited by-同舟云学术

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Microfluidic immunocapture of circulating pancreatic cells using parallel EpCAM and MUC1 capture: characterization, optimization and downstream analysis

Published:2014 Issue:10 Volume:14 Page:1775-1784
ISSN:1473-0197
Container-title:Lab Chip
language:en
Short-container-title:Lab Chip

Author:

Thege Fredrik I.¹²³⁴,Lannin Timothy B.⁵²³⁴,Saha Trisha N.⁶⁷⁸⁹¹⁰,Tsai Shannon⁶⁷⁸⁹,Kochman Michael L.⁶⁷⁸⁹,Hollingsworth Michael A.¹¹¹²¹³,Rhim Andrew D.⁶⁷⁸⁹¹⁰,Kirby Brian J.⁵²³⁴¹⁴

Affiliation:

1. Department of Biomedical Engineering

2. College of Engineering

3. Cornell University

4. Ithaca, USA

5. Sibley School of Mechanical & Aerospace Engineering

6. Gastroenterology Division

7. Department of Medicine

8. University of Pennsylvania

9. Philadelphia, USA

10. Division of Gastroenterology

11. Eppley Institute for Research in Cancer and Allied Diseases

12. University of Nebraska Medical Center

13. Omaha, USA

14. Division of Hematology and Medical Oncology

Abstract

Optimization of pancreatic CTC immunocapture and phenotyping in a microfluidic device.

Funder

National Cancer Institute

National Institute of Diabetes and Digestive and Kidney Diseases

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2014/LC/C4LC00041B

Reference47 articles.

1. Pancreatic Cancer in the General Population: Improvements in Survival Over the Last Decade

2. New-onset diabetes: a potential clue to the early diagnosis of pancreatic cancer

3. Circulating tumor cells: a window into cancer biology and metastasis

4. DETECTION OF DISSEMINATED TUMOR CELLS IN PERIPHERAL BLOOD

5. Detection and characterization of carcinoma cells in the blood

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