From ferrocene to fluorine-containing penta-substituted derivatives and all points in-between; or, how to increase the available chemical space-Reference-Cited by-同舟云学术

From ferrocene to fluorine-containing penta-substituted derivatives and all points in-between; or, how to increase the available chemical space

Published:2019 Issue:42 Volume:17 Page:9352-9359
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Tazi Mehdi¹²³⁴⁵,Erb William¹²³⁴⁵^ORCID,Roisnel Thierry¹²³⁴⁵^ORCID,Dorcet Vincent¹²³⁴⁵,Mongin Florence¹²³⁴⁵^ORCID,Low Paul J.⁶⁷⁸⁹^ORCID

Affiliation:

1. Univ Rennes

2. CNRS

3. ISCR (Institut des Sciences Chimiques de Rennes) - UMR 6226

4. F-35000 Rennes

5. France

6. School of Molecular Sciences

7. University of Western Australia

8. Crawley 6009

9. Australia

Abstract

The syntheses of di-, tri-, tetra- and pentasubstituted derivatives of fluoroferrocene from ferrocene are reported. These strategies enhance the available chemical space for future applications in medicinal and organic materials chemistry.

Funder

Ministère de l'Enseignement supérieur, de la Recherche et de l'Innovation

Université de Rennes 1

European Regional Development Fund

Centre National de la Recherche Scientifique

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C9OB01885A

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4. Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

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