An efficient enantioselective approach to multifunctionalized γ-butyrolactone: concise synthesis of (+)-nephrosteranic acid

Author:

Gehlawat Anju1234,Prakash Ranjana1234,Pandey Satyendra Kumar12345ORCID

Affiliation:

1. School of Chemistry and Biochemistry

2. Thapar Institute of Engineering and Technology

3. Patiala-147 001

4. India

5. Department of Chemistry

Abstract

A short, efficient and novel approach for multifunctionalized γ-butyrolactone paraconic acids and its application to the total synthesis of (+)-nephrosteranic acid from readily available PMB (R)-glycidyl ether as a starting material are described.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference77 articles.

1. The Renaissance of α-Methylene-γ-butyrolactones: New Synthetic Approaches

2. Paraconic Acids—The Natural Products from Lichen Symbiont

3. An update on bioactive plant lignans

4. S. S. C.Koch and A. R.Chamberlin , in Studies in Natural Product Chemistry , ed. Atta-ur-Rahman , Elsevier , New York , 1995 , vol. 16 , p. 687

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