All-in-one microfluidic device for on-site diagnosis of pathogens based on an integrated continuous flow PCR and electrophoresis biochip-Reference-Cited by-同舟云学术

All-in-one microfluidic device for on-site diagnosis of pathogens based on an integrated continuous flow PCR and electrophoresis biochip

Published:2019 Issue:16 Volume:19 Page:2663-2668
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Li Zhenqing¹²³⁴⁵^ORCID,Ju Ruixue¹²³⁴⁵,Sekine Shinichi⁶⁷⁸⁹¹⁰^ORCID,Zhang Dawei¹²³⁴⁵^ORCID,Zhuang Songlin¹²³⁴⁵,Yamaguchi Yoshinori¹¹¹²¹³⁵¹⁴^ORCID

Affiliation:

1. Engineering Research Centre of Optical Instrument and System, Ministry of Education

2. Key Lab of Optical Instruments and Equipment for Medical Engineering, Ministry of Education

3. Shanghai Key Lab of Modern Optical System

4. University of Shanghai for Science and Technology

5. Shanghai

6. Department of Preventive Dentistry

7. Graduate School of Dentistry

8. Osaka University

9. Osaka

10. Japan

11. Institute of Photonics and Bio-medicine (IPBM)

12. Graduate School of Science

13. East China University of Science and Technology

14. China

Abstract

A miniaturized device based on integrated continuous flow PCR and electrophoresis microfluidic chip was developed for diagnosis of pathogens. It dispensed with costly external precision syringe pump and can realize rapid DNA amplification and on-site PCR products detection.

Funder

National Natural Science Foundation of China

Science and Technology Commission of Shanghai Municipality

University of Shanghai for Science and Technology

National Basic Research Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2019/LC/C9LC00305C

Reference27 articles.