Vilsmeier–Haack reaction of 7-acetyl-2-arylindoles: a convenient method for the synthesis of 6-oxo-6H-pyrrolo[3,2,1-ij]quinoline-1,5-dicarbaldehydes-Reference-Cited by-同舟云学术

Vilsmeier–Haack reaction of 7-acetyl-2-arylindoles: a convenient method for the synthesis of 6-oxo-6H-pyrrolo[3,2,1-ij]quinoline-1,5-dicarbaldehydes

Published:2019 Issue:8 Volume:17 Page:2204-2211
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Mphahlele Malose J.¹²³⁴⁵^ORCID,Mmonwa Mmakwena M.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. College of Science

3. Engineering and Technology

4. University of South Africa

5. Florida 1710

Abstract

The 7-acetylindoles reacted with three Vilsmeier–Haack reagent derived formyl units to afford the 6-oxo-6H-pyrrolo[3,2,1-ij]quinoline-1,5-dicarbaldehydes in a single-pot operation.

Funder

University of South Africa

National Research Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C8OB03040E

Reference24 articles.

1. Fused Quinolines. Recent Synthetic Approaches to Azoloquinolines. A Review

2. Facile syntheses of 7,9-dimethoxypyrrolo[3,2,1-ij]quinolin-6-ones

3. Tricyclic amides: a new class of systemic fungicides active against rice blast disease

4. Pyrrolo[3,2,1- ij ]quinoline derivatives, a 5-HT 2c receptor agonist with selectivity over the 5-HT 2a receptor: potential therapeutic applications for epilepsy and obesity

5. Modifications of C-2 on the pyrroloquinoline template aimed at the development of potent herpesvirus antivirals with improved aqueous solubility

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