A novel pH-responsive hydrogel based on natural polysaccharides for controlled release of protein drugs

Author:

Xu Wenjin12345,He Xianran678910,Zhong Min1178910,Hu Xianming12345,Xiao Yuling12345

Affiliation:

1. State Key Laboratory of Virology

2. Ministry of Education Key Laboratory of Combinatorial Biosynthesis and Drug Discovery

3. Wuhan University School of Pharmaceutical Sciences

4. Wuhan 430071

5. China

6. Institute for Interdisciplinary Research

7. Jianghan University

8. Wuhan Economic and Technological Development Zone

9. Wuhan 430056

10. People’s Republic of China

11. School of Chemical and Environmental Engineering

Abstract

A biocompatible and biodegradable hydrogel based on a natural polysaccharide was prepared, characterized and confirmed to be an effective and “smart” carrier for controlled protein delivery.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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