Pd-Catalyzed carbonylative lactonization of 2-halidearomatic aldehydes with H<sub>2</sub>O as a nucleophile-Reference-Cited by-同舟云学术

Pd-Catalyzed carbonylative lactonization of 2-halidearomatic aldehydes with H₂O as a nucleophile

Published:2022 Issue:19 Volume:20 Page:3917-3921
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Si Min¹,Yan Jiaqi¹,Ding Yongzheng¹,Huang Hanmin¹²^ORCID

Affiliation:

1. Department of Chemistry, School of Chemistry and Material Science, Center for Excellence in Molecular Synthesis of CAS, University of Science and Technology of China, Hefei, 230026, P. R. China

2. State Key Laboratory of Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, P. R. China

Abstract

A palladium-catalyzed carbonylative lactonization reaction of 2-halidearomatic aldehydes and CO with H2O as a nucleophile is described, which provides a strategy for the synthesis of diversely substituted 3,3′-oxyphthalides and phthalides.

Funder

Chinese Academy of Sciences

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB00623E

Reference46 articles.

1. Synthesis and Modeling Studies with Monocyclic Analogues of Mycophenolic Acid

2. Chemistry and biological activities of naturally occurring phthalides

3. Chemistry and biological activities of naturally occurring phthalides

4. The Structural Diversity of Phthalides from the Apiaceae

5. Active Methylene Compounds in the Synthesis of 3-substituted Isobenzofuranones, Isoindolinones and Related Compounds

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