Carotane sesquiterpenoids A–G from the desert endophytic fungus <i>Fusarium</i> sp. HM 166-Reference-Cited by-同舟云学术

Carotane sesquiterpenoids A–G from the desert endophytic fungus Fusarium sp. HM 166

Published:2022 Issue:38 Volume:12 Page:24590-24595
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zhang Bing-Wen¹,Jiang Li¹,Li Zhuang¹,Gao Xue-Hui¹,Cao Fei¹,Lu Xin-hua²,Shen Wen-Bin²,Zhang Xue-Xia²,Kong Fan-Dong³,Luo Du-Qiang¹^ORCID

Affiliation:

1. College of Life Science, Key Laboratory of Microbial Diversity Research and Application of Hebei Province, Hebei University, Baoding 071002, People's Republic of China

2. New Drug Research & Development Center of North China Pharmaceutical Group Corporation, National Microbial Medicine Engineering & Research Center, Hebei Industry Microbial Metabolic Engineering & Technology Research Center, Key Laboratory for New Drug Screening Technology of Shijiazhuang City, Shijiazhuang 052165, Hebei, China

3. Key Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products, Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, School of Chemistry and Chemical Engineering, Guangxi Minzu University, Nanning 530006, Republic of China

Abstract

Seven undescribed carotane sesquiterpenoids were isolated from the endophytic fungi Fusarium sp. HM166. Single-crystal X-ray diffraction and ECD defined absolute configurations. Cytotoxicity for Huh-7, MCF-7, and MDA-MB-231 cancer cell lines and IDH1R132h mutant were studied.

Funder

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA02762C

Reference18 articles.

1. Cytotoxic and Other Metabolites of Aspergillus Inhabiting the Rhizosphere of Sonoran Desert Plants

2. Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019

3. Biology and chemistry of endophytes

4. Chaetoglobosin U, a Cytochalasan Alkaloid from Endophytic Chaetomium globosum IFB-E019

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