A photo-responsive self-healing hydrogel loaded with immunoadjuvants and MoS2 nanosheets for combating post-resection breast cancer recurrence

Author:

Wang Siyu1,Qian Zhuoping1,Xiao Huaxin1,Yang Guangwen2,Zhu Ziyi1,Gu Yubin1,Song Junjie1,Zhang Xin1,Huang Xinxuan1,Weng Lixing1,Gao Yu1ORCID,Yang Wenjing1ORCID,Wang Lianhui1ORCID

Affiliation:

1. State Key Laboratory for Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Jiangsu National Synergistic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts & Telecommunications, Nanjing 210023, China

2. Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu 210008, China

Abstract

A photo-responsive self-healing hydrogel-mediated photothermal therapy combined with immune checkpoint blockade effectively inhibited the recurrence of resected tumors, offering insights against post-resection breast cancer recurrence.

Funder

Natural Science Foundation of Jiangsu Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

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