Principles and methods used to grow and optimize crystals of protein–metallodrug adducts, to determine metal binding sites and to assign metal ligands-Reference-Cited by-同舟云学术

Principles and methods used to grow and optimize crystals of protein–metallodrug adducts, to determine metal binding sites and to assign metal ligands

Published:2017 Issue:11 Volume:9 Page:1534-1547
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Russo Krauss Irene¹²³⁴⁵^ORCID,Ferraro Giarita¹²³⁴⁵^ORCID,Pica Andrea⁶⁷⁸^ORCID,Márquez José A.⁶⁷⁸^ORCID,Helliwell John R.⁹¹⁰¹¹¹²¹³^ORCID,Merlino Antonello¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemical Sciences

2. University of Naples Federico II

3. Complesso Universitario di Monte Sant’Angelo

4. Napoli

5. Italy

6. EMBL Grenoble

7. 38042 Grenoble Cedex 9

8. France

9. School of Chemistry

10. Faculty of Engineering and Physical Sciences

11. University of Manchester

12. Manchester M13 9PL

13. UK

Abstract

Examples from the literature and experience in our own laboratory on the characterization of the interactions between biological macromolecules and metal-based drugs are provided.

Funder

Università degli Studi di Napoli Federico II

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2017/MT/C7MT00219J

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