Practical synthesis and cytotoxic evaluation of the pyrazino[1,2-b]-isoquinoline ring system
Author:
Affiliation:
1. Departamento de Química Orgánica
2. Instituto de Química
3. Universidad Nacional Autónoma de México
4. Circuito Exterior S.N.
5. Ciudad Universitaria
Abstract
A multicomponent three-step synthesis of pyrazino[1-2b]isoquinolines is described. A preliminary cytotoxic screening against cancer cell lines was performed.
Funder
Consejo Nacional de Ciencia y Tecnología
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB00431H
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