Ester coupling reactions – an enduring challenge in the chemical synthesis of bioactive natural products
Author:
Affiliation:
1. Chemical Biology Laboratory
2. Department of Chemistry
3. Aarhus University
4. Aarhus C
5. Denmark
Abstract
In this review we investigate the use of complex ester fragment couplings within natural product total syntheses. Using examples from the literature up to 2014 we illustrate the state-of-the-art as well as the challenges within this area of organic synthesis.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/NP/C4NP00106K
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