Translating endoplasmic reticulum biology into the clinic: a role for ER-targeted natural products?
Author:
Affiliation:
1. REQUIMTE/LAQV
2. Laboratório de Farmacognosia
3. Departamento de Química
4. Faculdade de Farmácia
5. Universidade do Porto
6. UCIBIO
7. REQUIMTE
8. Laboratório de Bioquímica
9. Departamento de Ciências Biológicas
Abstract
In this review, we present the current knowledge of ER biology and the hallmarks of ER stress, thus paving the way for presenting the natural products that have been described as being ER modulators, either stress inducers or ER protectors.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/NP/C4NP00102H
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