Nitroreductase-triggered activation of a novel caged fluorescent probe obtained from methylene blue-Reference-Cited by-同舟云学术

Nitroreductase-triggered activation of a novel caged fluorescent probe obtained from methylene blue

Published:2015 Issue:64 Volume:51 Page:12787-12790
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Bae Jungeun¹²³⁴⁵,McNamara Louis E.⁶³⁴⁵,Nael Manal A.⁷²³⁴⁵,Mahdi Fakhri⁸⁹¹⁰⁵,Doerksen Robert J.⁷²³⁴⁵,Bidwell Gene L.⁸⁹¹⁰⁵,Hammer Nathan I.⁶³⁴⁵,Jo Seongbong¹²³⁴⁵

Affiliation:

1. Department of Pharmaceutics and Drug Delivery

2. School of Pharmacy

3. The University of Mississippi

4. University

5. USA

6. Department of Chemistry and Biochemistry

7. Department of BioMolecular Sciences

8. Department of Neurology

9. The University of Mississippi Medical Center

10. Jackson

Abstract

A new fluorescent probe caged with a p-nitrobenzyl redox switch enables selective switching on of fluorescence by nitroreductase.

Funder

National Science Foundation

Medical Research and Materiel Command, U.S. Army Medical Department

National Institute for Health Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2015/CC/C5CC03824C

Reference27 articles.

1. Reductive Chemistry of the Novel Hypoxia-Selective Cytotoxin 5-[N,N-Bis(2-chloroethyl)amino]-2,4-dinitrobenzamide

2. NITROREDUCTASE: A PRODRUG-ACTIVATING ENZYME FOR CANCER GENE THERAPY

3. Development of a sensitive long-wavelength fluorogenic probe for nitroreductase: A new fluorimetric indictor for analyte determination by dehydrogenase-coupled biosensors

4. Nitroreductase-based GDEPT

5. The bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954)—II

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