Selenium deficiency caused hepatitis in chickens <i>via</i> the miR-138-5p/SelM/ROS/Ca<sup>2+</sup> overload pathway induced by hepatocyte necroptosis-Reference-Cited by-同舟云学术

Selenium deficiency caused hepatitis in chickens via the miR-138-5p/SelM/ROS/Ca²⁺ overload pathway induced by hepatocyte necroptosis

Published:2023 Issue:20 Volume:14 Page:9226-9242
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Sun Xinyue¹,Zhang Wenyue¹,Shi Xu¹,Wang Yuqi¹,Zhang Yilei¹,Liu Xiaojing¹,Xu Shiwen¹²^ORCID,Zhang Jiuli¹³

Affiliation:

1. College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, P. R. China

2. Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment, College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, P. R. China

3. Heilongjiang Polytechnic, Harbin 150030, P. R. China

Abstract

Selenium deficiency cause oxidative stress through upregulation of miR-138-5p targeting SelM, which disrupted Ca2+ and energy metabolic homeostasis allowing hepatocyte necroptosis leading to hepatitis in chickens.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D3FO00683B

Reference63 articles.

1. Methionine selenium antagonizes LPS‐induced necroptosis in the chicken liver via the miR‐155/TRAF3/MAPK axis

2. Serum selenium and non-alcoholic fatty liver disease (NAFLD) in U.S. adults: National Health and Nutrition Examination Survey (NHANES) 2011–2016

3. Selenium Deficiency and Endemic Heart Failure in China: A Case Study of Biogeochemistry for Human Health

4. Di-(2-ethyl hexyl) phthalate induces necroptosis in chicken cardiomyocytes by triggering calcium overload

5. Selenium Deficiency-Induced Apoptosis of Chick Embryonic Vascular Smooth Muscle Cells and Correlations with 25 Selenoproteins

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