An organocatalytic domino Michael addition strategy: construction of bispiro[oxindole-thiazolidinone-hexahydroxanthone]s with five contiguous stereocenters-Reference-Cited by-同舟云学术

An organocatalytic domino Michael addition strategy: construction of bispiro[oxindole-thiazolidinone-hexahydroxanthone]s with five contiguous stereocenters

Published:2020 Issue:37 Volume:18 Page:7373-7378
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Song Yong-Xing¹²³⁴,Lin Ye¹²³⁴,Yan Li⁵²⁶⁷⁴,Du Da-Ming¹²³⁴^ORCID

Affiliation:

1. School of Chemistry and Chemical Engineering

2. Beijing Institute of Technology

3. Beijing 100081

4. People's Republic of China

5. Analytical and Testing Center

6. Liangxiang Campus

7. Beijing 102488

Abstract

An efficient squaramide-catalyzed domino Michael addition for the stereoselective synthesis of bispiro[oxindole-thiazolidinone-hexahydroxanthone]s in good to excellent yields with excellent stereoselectivities was developed.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB01613F

Reference58 articles.

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2. Stereocontrolled synthesis of spirocyclics

3. A synthon approach to spiro compounds

4. Spiro Skeletons: A Class of Privileged Structure for Chiral Ligand Design

5. Selected Synthetic Strategies to Spirocyclics

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