Ammonium based stabilizers effectively counteract urea-induced denaturation in a small protein: insights from molecular dynamics simulations-Reference-Cited by-同舟云学术

Ammonium based stabilizers effectively counteract urea-induced denaturation in a small protein: insights from molecular dynamics simulations

Published:2017 Issue:83 Volume:7 Page:52888-52906
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Sarkar Soham¹²³⁴,Ghosh Soumadwip¹²³⁴,Chakrabarti Rajarshi¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. Indian Institute of Technology Bombay

3. Mumbai – 400076

4. India

Abstract

Room temperature ionic liquids (IL) and deep eutectic solvents (DES) are known to aid the conformational stability and activity of proteins and enzymes in aqueous solutions.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA10712A

Reference125 articles.

1. A Simple Method for Improving Protein Solubility and Long-Term Stability

2. Comparative analysis of naturally occurring L-amino acid osmolytes and their D-isomers on protection ofEscherichia coli against environmental stresses

3. Betaine protects urea-induced denaturation of myosin subfragment-1

4. Sucrose reduces the efficiency of protein denaturation by a chaotropic agent

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