Synthesis and evaluation of the biological activity of N′-[2-oxo-1,2 dihydro-3H-indol-3-ylidene] benzohydrazides as potential anticancer agents-Reference-Cited by-同舟云学术

Synthesis and evaluation of the biological activity of N′-[2-oxo-1,2 dihydro-3H-indol-3-ylidene] benzohydrazides as potential anticancer agents

Published:2015 Issue:56 Volume:5 Page:45492-45501
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Katiyar Arpit¹²³⁴⁵,Hegde Mahesh⁶⁷⁸⁴,Kumar Sujeet¹²³⁴,Gopalakrishnan Vidya⁹¹⁰⁴,Bhatelia Khyati D.⁶⁷⁸⁴,Ananthaswamy Kavya⁶⁷⁸⁴,Ramareddy Sureshbabu A.¹²³⁴,De Clercq Erik¹¹¹²¹³¹⁴,Choudhary Bibha⁹¹⁰⁴,Schols Dominique¹¹¹²¹³¹⁴,Raghavan Sathees C.⁶⁷⁸⁴,Karki Subhas S.¹²³⁴

Affiliation:

1. Department of Pharmaceutical Chemistry

2. KLE University's College of Pharmacy

3. Bangalore-560 010

4. India

5. Department of Pharmacy and Medical Science

6. Department of Biochemistry

7. Indian Institute of Science

8. Bangalore-560012

9. Institute of Bioinformatics and Applied Biotechnology

10. Bangalore 560 100

11. Rega Institute for Medical Research

12. KU Leuven

13. B-3000 Leuven

14. Belgium

Abstract

New N′-[2-oxo-1,2-dihydro-3H-indol-3-ylidene]benzohydrazide derivatives were synthesized and evaluated for their cytotoxic properties against murine leukemia, L1210, human leukemia, REH, K562 and CEM and human cervix carcinoma, HeLa cells.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA01528F

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