Biological sealing and integration of a fibrinogen-modified titanium alloy with soft and hard tissues in a rat model-Reference-Cited by-同舟云学术

Biological sealing and integration of a fibrinogen-modified titanium alloy with soft and hard tissues in a rat model

Published:2021 Issue:15 Volume:9 Page:5192-5208
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Wang Xiuli¹²³⁴⁵,Lei Xing⁶⁷⁸⁹⁵,Yu Yue¹²³⁴⁵,Miao Sheng⁶⁷⁸⁹⁵,Tang Jingyu¹²³⁴⁵,Fu Ye¹²³⁴⁵,Ye Kai¹²³⁴⁵,Shen Yang¹²³⁴⁵,Shi Jiayue¹²³⁴⁵,Wu Hao⁶⁷⁸⁹⁵,Zhu Yi¹²³⁴⁵,Yu Lin¹²³⁴⁵^ORCID,Pei Guoxian⁶⁷⁸⁹⁵^ORCID,Bi Long⁶⁷⁸⁹⁵,Ding Jiandong¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Molecular Engineering of Polymers

2. Department of Macromolecular Science

3. Fudan University

4. Shanghai 200438

5. China

6. Department of Orthopedics

7. Xijing Hospital

8. The Fourth Military Medical University

9. Xi'an 710032

Abstract

A Ti–6Al–4V alloy was modified with fibrinogen as mediated by polydopamine, and the skin-implant interface was examined after transcutaneous implantation. The surface modification could inhibit epithelial downgrowth and promote bone regeneration.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D1BM00762A

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1. Applications and failure modes of percutaneous devices: A review

2. Strategies for Optimizing the Soft Tissue Seal around Osseointegrated Implants