Cyclamenols E and F, two diastereoisomeric bicyclic macrolactams with a cyclopentane moiety from an Antarctic Streptomyces species-Reference-Cited by-同舟云学术

Cyclamenols E and F, two diastereoisomeric bicyclic macrolactams with a cyclopentane moiety from an Antarctic Streptomyces species

Published:2020 Issue:2 Volume:7 Page:310-317
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Shen Jingjing¹²³⁴⁵,Wang Jie¹²³⁴⁵,Chen Hao⁶⁷⁸⁹¹⁰,Wang Yi¹²³⁴⁵,Zhu Weiming¹²³⁴⁵^ORCID,Fu Peng¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Marine Drugs

2. Ministry of Education of China

3. School of Medicine and Pharmacy

4. Ocean University of China

5. Qingdao 266003

6. Key Laboratory of Marine Bioactive Substances

7. First Institute of Oceanography

8. Ministry of Natural Resources of China

9. Qingdao 266061

10. China

Abstract

A new bicyclic macrolactam with selective inhibition against N87 cells, together with its diastereoisomer, was isolated from an Antarctic Streptomyces species.

Funder

National Basic Research Program of China

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QO/C9QO01215J

Reference23 articles.

1. Diversifying microbial natural products for drug discovery

2. Microbial natural products: molecular blueprints for antitumor drugs

3. Terrestrial Microorganisms: Cell Factories of Bioactive Molecules with Skin Protecting Applications

4. Microbial drug discovery: 80 years of progress

5. Opportunities for natural products in 21st century antibiotic discovery

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