Intracellular delivery of therapeutic proteins through N-terminal site-specific modification-Reference-Cited by-同舟云学术

Intracellular delivery of therapeutic proteins through N-terminal site-specific modification

Published:2020 Issue:77 Volume:56 Page:11473-11476
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Liew Si Si¹²³,Zhang Chengwu⁴⁵⁶⁷,Zhang Jie⁸⁹¹⁰¹¹,Sun Hongyan⁸⁹¹⁰¹¹^ORCID,Li Lin⁴⁵⁶⁷^ORCID,Yao Shao Q.¹²³^ORCID

Affiliation:

1. Department of Chemistry

2. National University of Singapore

3. Singapore

4. Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM)

5. Nanjing Tech University

6. Nanjing 211816

7. P. R. China

8. Department of Chemistry and COSDAF (Centre of Super-Diamond and Advanced Films)

9. City University of Hong Kong

10. Kowloon

11. China

Abstract

Adopting orthogonal dual-labeling strategies, a cell-permeable RNase A prodrug was designed for ROS-responsive targeted cancer therapy.

Funder

Economic Development Board - Singapore

National Research Foundation Singapore

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CC/D0CC04728G

Reference30 articles.

1. Protein therapeutics: a summary and pharmacological classification

2. Bypassing Endocytosis: Direct Cytosolic Delivery of Proteins

3. Antibody Delivery for Intracellular Targets: Emergent Therapeutic Potential

4. Promises and Pitfalls of Intracellular Delivery of Proteins

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