Synthesis and photodynamic effects of new porphyrin/4-oxoquinoline derivatives in the inactivation of S. aureus

Author:

Sagrillo Fernanda Savacini12345,Dias Cristina56789,Gomes Ana T. P. C.102114ORCID,Faustino Maria A. F.1234ORCID,Almeida Adelaide102114ORCID,Gonçalves de Souza Alan56789,Costa Amanda Rodrigues Pinto56789,Boechat Fernanda da Costa Santos56789,Bastos Vieira de Souza Maria Cecília56789,Neves Maria G. P. M. S.1234ORCID,Cavaleiro José A. S.1234

Affiliation:

1. QOPNA & LAQV-REQUIMTE and Chemistry Department

2. University of Aveiro

3. 3810-193 Aveiro

4. Portugal

5. Programa de Pós-Graduação em Química

6. Instituto de Química

7. Universidade Federal Fluminense

8. Rio de Janeiro

9. Brazil

10. Department of Biology and CESAM

11. Aveiro

Abstract

New porphyrin/4-oxoquinoline conjugates were synthesized and shown to be excellent photosensitizing agents in the inactivation of S. aureus by the antimicrobial photodynamic therapy protocol.

Funder

Universidade de Aveiro

Centro de Estudos Ambientais e Marinhos, Universidade de Aveiro

European Regional Development Fund

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Universidade Federal Fluminense

Fundação para a Ciência e a Tecnologia

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry

Reference50 articles.

1. Vancomycin: A 50-Year Reassessment

2. R. O. A. Resistance , Tackling Drug-resistant Infections Globally: Final Report and Recommendations , 2016

3. Potential applications of porphyrins in photodynamic inactivation beyond the medical scope

4. Upconversion in photodynamic therapy: plumbing the depths

5. G. Jori , M.Camerin , M.Soncin , L.Guidolin and O.Coppellotti , Antimicrobial Photodynamic Therapy: Basic Principles , in Photodynamic Inactivation of Microbial Pathogens: Medical and Environmental Applications , The Royal Society of Chemistry , 2011 , ch. 1, vol. 11 , pp. 1–18

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