Exploring the BSA- and DNA-binding, cytotoxicity, and cell cycle evaluation of ternary copper(<scp>ii</scp>)/diimine complexes with N,N-dibenzyl-N′-benzoylthiourea as promising metallodrug candidates-Reference-Cited by-同舟云学术

Exploring the BSA- and DNA-binding, cytotoxicity, and cell cycle evaluation of ternary copper(ii)/diimine complexes with N,N-dibenzyl-N′-benzoylthiourea as promising metallodrug candidates

Published:2024 Issue:31 Volume:53 Page:12951-12961
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Gonçalves Guilherme R.¹,Teixeira Tamara¹,Bezerra Daniel P.²^ORCID,Soares Milena B. P.²,Silva Valdenizia R.²,Santos Luciano de S.²,Batista Alzir A.³^ORCID,Oliveira Katia M.¹⁴^ORCID,Correa Rodrigo S.¹^ORCID

Affiliation:

1. Departamento de Química, ICEB, Universidade Federal de Ouro Preto – UFOP, CEP 35400-000, Ouro Preto, MG, Brazil

2. Instituto Gonçalo Moniz – Fundação Oswaldo Cruz (IGM-FIOCRUZ-BA), CEP 40296-710, Salvador, BA, Brazil

3. Departamento de Química, Universidade Federal de São Carlos – UFSCar, CP 676, CEP 13561-901, São Carlos, SP, Brazil

4. Instituto de Química, Universidade de Brasília – UnB, Campus Darcy Ribeiro, CEP 70910-900, Brasília, DF, Brazil

Abstract

Four new copper(ii) complexes were synthesized and characterized with the general formula [Cu(N–N)(Th)(NO3)], where N–N corresponds to the N-heterocyclic ligands and Th represents the N,N-dibenzyl-N′-benzoylthiourea.

Funder

Fundação de Amparo à Pesquisa do Estado de Minas Gerais

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Apoio à Pesquisa do Distrito Federal

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/DT/D4DT01152J

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