A Brønsted acid-catalyzed thioacid addition to in situ-generated aldimine for the synthesis of isoindolinones with the N,S-acetal framework

Author:

Sadhu Milon M.1ORCID,Khajuria Chhavi2,Singh Vinod K.12ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal, MP-462 066, India

2. Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur, UP-208 016, India

Abstract

A Brønsted acid catalyzed three-component reaction has been developed for the synthesis of isoindolinones containing N,S-acetal framework.

Funder

Department of Science & Technology, Ministry of Science and Technology, India

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference50 articles.

1. P.Metzner and A.Thuillier , Sulfur Reagents in Organic Synthesis , Academic Press , New York , 1994

2. A.Nudelman , The Chemistry of Optically Active Sulfur Compounds , Gordon and Breach , New York , 1984

3. C.Chatgilialoglu and K.-D.Asmus , Sulfur-Centered Reactive Intermediates in Chemistry and Biology , Springer , New York , 1991

4. Recent chemistry of the β-lactam antibiotics

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