Protein binding studies with human serum albumin, molecular docking and in vitro cytotoxicity studies using HeLa cervical carcinoma cells of Cu(ii)/Zn(ii) complexes containing a carbohydrazone ligand-Reference-Cited by-同舟云学术

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Protein binding studies with human serum albumin, molecular docking and in vitro cytotoxicity studies using HeLa cervical carcinoma cells of Cu(ii)/Zn(ii) complexes containing a carbohydrazone ligand

Published:2020 Issue:9 Volume:49 Page:2947-2965
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Parsekar Sidhali U.¹²³⁴,Velankanni Priyanka¹²³⁴,Sridhar Shruti¹²³⁴⁵,Haldar Paramita¹²³⁴,Mate Nayan A.⁵²⁴,Banerjee Arnab⁵²⁴,Sudhadevi Antharjanam P. K.⁶⁷⁸⁴,Koley Aditya P.⁹²³⁴^ORCID,Kumar Manjuri¹²³⁴

Affiliation:

1. Department of Chemical Engineering

2. Birla Institute of Technology and Science-Pilani

3. Zuarinagar

4. India

5. Department of Biological Sciences

6. Sophisticated Analytical Instrument Facility

7. Indian Institute of Technology-Madras

8. Chennai 600 036

9. Department of Chemistry

Abstract

Cu(ii) and Zn(ii) complexes show very strong binding with human serum albumin and display remarkable cytotoxicity against the HeLa cell line.

Funder

Department of Science and Technology, Ministry of Science and Technology

Birla Institute of Technology and Science, Pilani

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/DT/C9DT04656A

Reference97 articles.

1. The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs

2. Inhibition of transcription by platinum antitumor compounds

3. Structure, Recognition, and Processing of Cisplatin−DNA Adducts

4. The status of platinum anticancer drugs in the clinic and in clinical trials

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