First total synthesis of fuzanins C, D and their analogues as anticancer agents-Reference-Cited by-同舟云学术

First total synthesis of fuzanins C, D and their analogues as anticancer agents

Published:2014 Issue:16 Volume:4 Page:8365-8375
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Kumar S. Naveen¹²³,Pavan Kumar C. H. N. S. Sai¹²³,Srihari E.¹²³,Kancharla Sravani⁴⁵,Srinivas Kolupula⁴⁵,Shrivastava Shweta⁴⁵,Naidu V. G. M.⁴⁵,Jayathirtha Rao V.¹²³⁴⁵

Affiliation:

1. Crop Protection Chemicals Division

2. Indian Institute of Chemical Technology

3. Hyderabad 500007, India

4. National Institute of Pharmaceutical Education and Research (NIPER)

5. Hyderabad 500 037, India

Abstract

Total synthesis of fuzanins C, D and their quinoline analogues has been accomplished from readily available starting materials. Synthesis of fuzanin D described here also serves to establish its absolute configuration. All compounds were screened for anticancer activity on four cancer cell lines. The quinoline analogues 4d, 4c, 3c are relatively more potent.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/RA/C3RA47263A

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